The results are incredible, especially when paired with products like PDRN, neurotoxins, exosomes, Sculptra, and dermal fillers. I love how versatile and easy it is to use! Dermoelectroporation needle skin baggy eyes wrinkles hair scalp free Electroporation drug delivery system dds dep ultrasound iontophoresis no pain no swelling no needles no downtime no pain
2025 DermaElectroporation DEP Needle Free Skin Rejuvenation Machine
2025 DermaElectroporation DEP Needle Free Skin Rejuvenation Machine
2025 DermaElectroporation DEP Needle Free Skin Rejuvenation Machine
2025 DermaElectroporation DEP Needle Free Skin Rejuvenation Machine
2025 DermaElectroporation DEP Needle Free Skin Rejuvenation Machine
2025 DermaElectroporation DEP Needle Free Skin Rejuvenation Machine

2025 DermaElectroporation DEP Needle Free Skin Rejuvenation Machine

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$2,250.00
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$2,250.00
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we ship worldwide and will ship outlet plug for customer’s country on order

***you must use BLT Numbing Cream Benzocaine/Lidocaine/Tetracaine with machine. BLT Cream can be found on Amazon***

DermaElectroporation® (DEP) is a patented, proprietary technology that utilizes the skins water based “channels” to allow ionic drug solutions to penetrate due to controlled “electroporation-like” continuous reversed polarity electrical pulses. Because of this, DermoElectroPoration® is able to control the average pulse value and vary the pulse shape according to the skin’s specific electrical impedance. We call this Predictive Permeation® .

DermaElecteoporation® promotes the transdermal delivery of both micro- and macro molecules (up to 2 million Dalton weight) safely into the body without the need of modifying the ionic drug solution pH, as with traditional iontophoresis. DermaElectroporation® does not require a pH compensation patch, driving gels, or pre-charged ions.

Unlike traditional iontophoresis, DermaElectroporation® does not have an electrolysis reaction at the site of the electrodes. There is no degradation of the molecule being delivered. This means that both positive and negative ions of the drug are delivered into the body – the drug is delivered as a whole.

No erythema.
No edema.
No risk of infection
DermaElectroporation® is the only transdermal delivery device FDA cleared for the local administration of ionic drug solutions into the body for medical purposes and can be used as an alternative to injections.

DermaElectroporation® increases the skin’s permeability by using the skin’s water based channels opened by a particular controlled current delivered to the patient, therefore allowing the substances to be absorbed by the hypodermis and muscle membranes.


Scientific Principles

Electrical Current Pulses flowing through the extra cellular matrix (mainly composed by water, ions, and glycosaminoglycans) produce a transient change in the microstructure.

Long-chained glycosaminoglycans orient themselves to create “channels” (water-based ones) allowing the delivery of macromolecules through the skin.

No cell injury (i.e. fragmentation of cytoplasm or nucleus, abnormalities of membrane due to low current intensity used) and no endothelial or micro-vascular damage occurs.

Features and Benefits of DermaElectroporation®

No needles.No pain. No downtime.

Your patients can walk out from this non-invasive procedure, put on makeup and go back to work. No redness, no stinging, just results.

Safe on all Fitzpatrick Scale Skin Types.

Any age, any color. Ability to infuse a wide variety of modalities into different layers of the skin and Sub-Q for maximum efficacy.


One device.
Face, Hair, Body.

Can be used for skin rejuvenation, hair restoration and body treatments, all in one device.

Applications:

FACE & NECK REJUVENATION

Infuse anti-aging protocols.

Hyaluronic Acid, peptides, PRP/PRF, exosomes, Vitamin C, toxins, and more!

HAIR & SCALP RESTORATION

No more needles.

Give your hair restoration patients your same protocols without the pain!

ACCELERATES WOUND HEALING

Reducing downtime.

Accelerates wound healing and may cut recovery time of current procedures in half.

Protocol:

1X Per week for 6 weeks with 1X per month maintenance 

 

Testimonial:

“First of all I NEVER agree to have my procedure pictures posted on a website but here I am breaking my rules because I feel like I FINALLY found the rejuvenation treatment for me! I’ve been burned so many times with expensive procedures that likely have photo-shopped before and after pics and I fall for it every time. I’ve had bad chemical peels which left me disfigured, Ultherapy which was beyond painful and left me with thin skin on my forehead, nevermind that the practitioner forgot to do even passes leaving my face lopsided. Then I’ve tried to fix that issue with Botox but experienced horrible facial drooping so I stopped trying to fix it. Fillers always left me looking overfilled and unnatural.

Regardless of the tens of thousands of dollars on all things related to my face, I got to a point where I gave up on all procedures out of frustration from my results. That is until I discovered the DEP Facial. I’ll admit I was quite dubious at first based on my past experiences, but thankfully that has changed within a short amount of time. It’s been less than a week and I’m in awe of what I see in the mirror and know this will be the facial I’ll be doing moving forward!”

Jennifer Hnat, RDN


Customer Reviews

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K
Kristen Dee NP
More clients scheduled per day vs needles

“The DEP device has been a game-changer for our practice. It’s lightweight, painless, and needleless, making it a client favorite. We use it for everything from scalp treatments to hyperhidrosis, as well as full facial and neck treatments. The results are incredible, especially when paired with products like PDRN, neurotoxins, exosomes, Sculptra, and dermal fillers. I love how versatile and easy it is to use!”